21c Museum Hotel Louisville

Rewarding stay available now.

21c Museum Hotel Louisville recently joined The Hotel Collection. While we are finalizing this profile page, 21c Museum Hotel Louisville is already available for bookings through American Express Travel — and offers elevated benefits to eligible Card Members with every stay of two nights or more. Check back soon for detailed descriptions and photos.

Location of 21c Museum Hotel Louisville

700 W Main St. Louisville, Kentucky 40202 United States

Louisville International Standiford Field.

THE HOTEL COLLECTION

At 21c Museum Hotel Louisville, Platinum Card® Members staying 2+ nights receive:*

For stays at 21c Museum Hotel Louisville beginning on 1/1/27, Platinum Card® Members staying 2+ nights receive:*

Room upgrade available at check-in, when available¹
Hotel Credit: $100 property credit to spend on qualifying dining, spa, and resort activities ²
Hotel Credit: $100 property credit to spend on qualifying dining, spa, and resort activities ²
12pm check-in, when available
Late check-out, when available

¹A one category room upgrade is based on availability and eligibility at time of check-in.
²Varies by property and facilities available.

Call Platinum Travel Service at 1-800-263-1616 to book this hotel and receive their benefits from The Hotel Collection.